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ProductsBack/Compound 34 [564462-36-8]
Chemical Structure
Chemical Structure
Chemical Structure

Compound 34 [564462-36-8]

Research Use Only
AG-CR1-0007
AdipoGen Life Sciences
CAS Number564462-36-8
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight543.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Compound 34 [564462-36-8]
  • Delivery Days Customer
    10
  • CAS Number
    564462-36-8
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C31H24F3N3O3
  • Molecular Weight
    543.5
  • Scientific Description
    Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06 nM) [1]. - Chemical. CAS: 564462-36-8. Formula: C31H24F3N3O3. MW: 543.5. Cell permeable, highly potent inhibitor of gamma-secretase (IC50 = 0.06 nM).
  • SMILES
    OC[C@H]([C@H](C(=O)N[C@H]1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC=C2)C1=CC=C(F)C=C1)C1=CC=C(F)C(F)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Design and synthesis of highly potent benzodiazepine gamma-secretase inhibitors: preparation of (2S,3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement: I. Churcher, et al.; J. Med. Chem 46 2275 (2003)