Compound 401 [168425-64-7]
ORB146120
CAS Number168425-64-7
Product group Chemicals
Molecular Weight281.3092
Overview
- SupplierBiorbyt
- Product NameCompound 401 [168425-64-7]
- Delivery Days Customer16
- CAS Number168425-64-7
- CertificationResearch Use Only
- Molecular FormulaC16H15N3O2
- Molecular Weight281.3092
- Scientific DescriptionCompound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over FRAP (mTOR) (IC50 = 5.3 microM).
- SMILESO1C([H])([H])C([H])([H])N(C2=C([H])C(N3C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C4C3=N2)=O)C([H])([H])C1([H])[H]
- UNSPSC12352200