Conopeptide rho-TIA

MedChem Express

Conopeptide rho-TIA

14

Research Use Only

C105H160N36O21S4

2390.88

Conopeptide rho-TIA is a peptide derived from the venom contained in the predatory sea snail Conus tulipa, has highly selective and noncompetitive inhibitor at human alpha1B-Adrenergic Receptor. Conopeptide rho-TIA acts a competitive inhibitor at human alpha1A-Adrenergic Receptor and alpha1D-Adrenergic Receptor. Conopeptide rho-TIA binds to each subtype and may provide useful information for the development of novel alpha1-Adrenergic Receptor subtype-selective drugs[1].

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CSSC[C@@](NC([C@@H](NC1=O)C)=O)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CC3=CN=CN3)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(N[C@](CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC2=O)CCCCN)=O)CCCCN)=O)CC4=CC=CC=C4)=O)C(N)=O)([

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