Contactin 1 antibody

GeneTex

Contactin 1 antibody

9

WB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Polyclonal

2.25 mg/ml

Unconjugated

Cntn1

contactin 1

AW495098; CN; CNTN; contactin-1; F3ca; F3cam; neural cell surface protein F3; u; usl

Rabbit

IgG

Contactin-1

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.

Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203