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Copper Transporting ATPase 2 Antibody: HRP

ORB149812
Biorbyt
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP7B
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Copper Transporting ATPase 2 antibody
  • Delivery Days Customer
    10
  • Application Supplier Note
    1 microg/ml of SMC-399 was sufficient for detection of Copper-transporting ATPase2 in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Applications Supplier
    WB (1:1000), ICC/IF (1:100) ELISA, IHC, WB
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    L62/29 (Formerly sold as S62-29)
  • Concentration
    1 mg/ml
  • Conjugate
    HRP
  • Gene ID540
  • Target name
    ATP7B
  • Target description
    ATPase copper transporting beta
  • Target synonyms
    ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; copper pump 2; copper-transporting ATPase 2; copper-transporting protein ATP7B; PWD; WC1; WD; Wilson disease-associated protein; WND
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDB7ZLR4
  • Protein Name
    ATP7B protein
  • Scientific Description
    Mouse monoclonal to Copper Transporting ATPase 2 (HRP). The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilsons disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage..
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    See Manual
  • UNSPSC
    12352203