Copper Transporting ATPase 2 Antibody: HRP
ORB149812
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP7B
Overview
- SupplierBiorbyt
- Product NameCopper Transporting ATPase 2 antibody
- Delivery Days Customer10
- Application Supplier Note1 microg/ml of SMC-399 was sufficient for detection of Copper-transporting ATPase2 in 20 microg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- Applications SupplierWB (1:1000), ICC/IF (1:100) ELISA, IHC, WB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDL62/29 (Formerly sold as S62-29)
- Concentration1 mg/ml
- ConjugateHRP
- Gene ID540
- Target nameATP7B
- Target descriptionATPase copper transporting beta
- Target synonymsATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; copper pump 2; copper-transporting ATPase 2; copper-transporting protein ATP7B; PWD; WC1; WD; Wilson disease-associated protein; WND
- HostMouse
- IsotypeIgG1
- Protein IDB7ZLR4
- Protein NameATP7B protein
- Scientific DescriptionMouse monoclonal to Copper Transporting ATPase 2 (HRP). The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilsons disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage..
- ReactivityHuman, Mouse, Rat
- Storage InstructionSee Manual
- UNSPSC12352203