Western blot All lanes: COPS3 antibody at 3.41microg/ml Lane 1: MCF-7 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: 293T whole cell lysate Lane 4: HT29 whole cell lysate Lane 5: Mouse heart tissue Lane 6: Mouse brain tissue Lane 7: Mouse ovarian tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48, 46 kDa Observed band size: 48 kDa

COPS3 Antibody

CSB-PA892483ESR1HU

ApplicationsImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetCOPS3

Overview

Supplier
Cusabio
Product Name
COPS3 Antibody
Delivery Days Customer
20
Applications
ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID8533
Target name
COPS3
Target description
COP9 signalosome subunit 3
Target synonyms
COP9 complex subunit 3; COP9 constitutive photomorphogenic homolog subunit 3; COP9 signalosome complex subunit 3; CSN3; JAB1-containing signalosome subunit 3; SGN3; signalosome subunit 3
Host
Rabbit
Isotype
IgG
Protein IDQ9UNS2
Protein Name
COP9 signalosome complex subunit 3
Scientific Description
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

COPS3 Antibody

Large volume orders?

Overview