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ProductsBack/COPS8 Antibody, HRP conjugated

COPS8 Antibody, HRP conjugated

Research Use Only
CSB-PA860346LB01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetCOPS8
Price on request
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    COPS8 Antibody, HRP conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    HRP
  • Gene ID10920
  • Target name
    COPS8
  • Target description
    COP9 signalosome subunit 8
  • Target synonyms
    COP9; COP9 constitutive photomorphogenic homolog subunit 8; COP9 homolog; COP9 signalosome complex subunit 8; CSN8; hCOP9; JAB1-containing signalosome subunit 8; SGN8; signalosome subunit 8
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ99627
  • Protein Name
    COP9 signalosome complex subunit 8
  • Scientific Description
    Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203