Camostat (mesylate) [59721-29-8]

Catalog number: HY-13512_100mg
Brand: MedChem Express
Packing: 100 mg
Other sizes: Other sizes available
Price: € 202.00
Expected delivery time: 10 days

Product specifications for - Camostat (mesylate) [59721-29-8]

Product group: Corona Related Products
Category: Other
CAS No.: 59721-29-8
Purity: >98%
Molecular Formula: C21H26N4O8S
Molecular weight: 494.52
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Scientific information: 
Scientific info: Camostat Mesylate(FOY305, FOY-S980) is a trypsin-like protease inhibitor Target: Trypsin-like protease Camostat mesilate (500 mM) inhibits generation of TGF-beta by suppressing plasmin activity and reduces the activity of TGF-beta, which blocks in vitro activation of HSCs [1]. Camostat mesilate (20 mM) combined with insulin results a significant hypoglycemic effect following large intestinal administration. Camostat mesilate (20 mM) is effective in reducing insulin degradation in both small and large intestinal homogenates of rats [2]. Camostat mesilate (2 mM) inhibits MCP-1 and TNF- production in activated rat monocytes. Camostat mesilate (2 mM) inhibits proliferation and MCP-1 production of cultured rat PSCs. Camostat mesilate (1 mg/g) prevents pancreatic atrophy and improves pancreatic exocrine function of rat chronic pancreatitis induced by DBTC. Camostat mesilate (1 mg/g) inhibits chronic inflammation and pancreatic fibrosis induced by DBTC. Camostat mesilate (1 mg/g) inhibits the development of pancreatic fibrosis and PSCs activation in the pancreas induced by DBTC. Camostat mesilate (1 mg/g) suppresses monocytes infiltration and inhibits MCP-1 expression both in serum and in pancreatic tissue [3].
Safety information: 
Additional information: 
Synonyms: HY-13512
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Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121. Read more
Nature. 2022 Jan 21. Read more
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Cell Discov. 2021 Dec 14;7(1):119. Read more
SSRN. 2020 Jun. Read more
Research Square Preprint. 2022 Jan. Read more
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. 2020 Sep. Read more
Eur J Med Chem. 2021, 113683. Read more
Biosaf Health. 3 January 2022. Read more