Hydroxychloroquine sulfate [747-36-4]

Catalog number: HY-B1370_10mM
Brand: MedChem Express
Packing: 10 mM
Other sizes: 50 mg
Price: € 95.00
Expected delivery time: 10 days

Product specifications for - Hydroxychloroquine sulfate [747-36-4]

Product group: Corona Related Products
Category: Other
CAS No.: 747-36-4
Molecular Formula: C18H28ClN3O5S
Molecular weight: 433.95
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Scientific information: 
Scientific info: Hydroxychloroquine sulfate is a synthetic antimalarial drug which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. IC50 & Target: Antimalarial[1], TLR7/9[2] In Vitro: Hydroxychloroquine sulfate is a synthetic antimalarial drug derived from 4-aminoquinoline, it has been used for several decades for the treatment of some rheumatic diseases such as rheumatoid arthritis (RA)[1]. Five micromolar Hydroxychloroquine sulfate or chloroquine also has no measurable effect on intracellular pH, although these concentrations can inhibit TLR9 or 7 signaling induced by DNA or RNA ligands[2]. In Vivo: Hydroxychloroquine sulfate is prescribed for the treatment of lupus, and both Hydroxychloroquine sulfate and its analog chloroquine inhibit TLR7 and 9 signaling[2].
Safety information: