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Ruxolitinib [941678-49-5]

Research Use Only
HY-50856
MedChem Express
CAS Number941678-49-5
Product group Chemicals
Estimated Purity98.11%
Molecular Weight306.37
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ruxolitinib [941678-49-5]
  • Delivery Days Customer
    10
  • CAS Number
    941678-49-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.11%
  • Molecular Formula
    C17H18N6
  • Molecular Weight
    306.37
  • Scientific Description
    Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.
  • SMILES
    N#CC[C@H](C1CCCC1)N2N=CC(C3=C4C=CNC4=NC=N3)=C2
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200