Ruxolitinib [941678-49-5]
HY-50856
CAS Number941678-49-5
Product group Chemicals
Estimated Purity98.11%
Molecular Weight306.37
Overview
- SupplierMedChem Express
- Product NameRuxolitinib [941678-49-5]
- Delivery Days Customer10
- CAS Number941678-49-5
- CertificationResearch Use Only
- Estimated Purity98.11%
- Molecular FormulaC17H18N6
- Molecular Weight306.37
- Scientific DescriptionRuxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy.
- SMILESN#CC[C@H](C1CCCC1)N2N=CC(C3=C4C=CNC4=NC=N3)=C2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200