COX-1-IN-1 [1369503-03-6]

TargetMol Chemicals

COX-1-IN-1 [1369503-03-6]

16

Research Use Only

C20H21NO3

323.39

COX-1-IN-1 (compound 15a) selectively inhibits cyclooxygenase (COX), exhibiting an IC50 of 0.23 microM for COX-1 and greater than 50 microM for COX-2, resulting in a selectivity index (COX-2 IC50/COX-1 IC50) of 217. Additionally, COX-1-IN-1 effectively inhibits platelet aggregation [1].

CC1=C(C(=NO1)C2=CC=C(OCC)C=C2)C3=CC=C(OCC)C=C3

-20°C

51202000