CP-316819

MedChem Express

CP-316819 [186392-43-8]

10

186392-43-8

Research Use Only

99.0

C21H22ClN3O4

415.87

CP 316819 is a potent glycogen phosphorylase (GPase) inhibitor with antihyperglycemic effect ( IC 50 values are 17 and 34 nM against human skeletal muscle glycogen phosphorylase (huSMGPa) and liver glycogen phosphorylase (huLGPa) respectively).CP 316819 causes glycogen accumulation under normoglycemic conditions but permits glycogen utilization when glucose concentrations are low.CP-316819 prevents neuronal cell death and maintains brain electrical currents [1] [2] .

CON(C)C([C@H](O)[C@H](CC1=CC=CC=C1)NC(C2=CC3=CC(Cl)=CC=C3N2)=O)=O

-20°C,2°C to 8°C

12352200