CRHR1 Antibody, HRP conjugated

Cusabio

CRHR1 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

CRHR1

corticotropin releasing hormone receptor 1

corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; CRF1; CRF-R; CRFR1; CRF-R1; CRF-R-1; CRFR-1; CRHR; CRH-R1; CRH-R-1; CRHR1L; seven transmembrane helix receptor

Rabbit

IgG

Corticotropin-releasing factor receptor 1

G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

Human

-20°C or -80°C

12352203