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Crobenetine (hydrochloride)

Research Use Only
HY-16923A
MedChem Express
Molecular Weight416.00
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Crobenetine (hydrochloride)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C25H34ClNO2
  • Molecular Weight
    416.00
  • Scientific Description
    Crobenetine hydrochloride (BIII-890 hydrochloride) is the hydrochloride form of Crobenetine (HY-16923). Crobenetine hydrochloride is a selective inhibitor for Na+ channel. Crobenetine hydrochloride displaces 3HBTX from site 2 of the Na+ channel (IC50=49 nM) in rat brain synaptosomes, exhibits only low binding affinity for other receptors and ion channels. Crobenetine hydrochloride protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents[1].
  • SMILES
    OC1=C2C([C@@]3(CCN([C@]([H])(C2)C3(C)C)C[C@H](C)OCC4=CC=CC=C4)C)=CC=C1.Cl
  • UNSPSC
    12352200