Bio-Connect

CRTAM Polyclonal Antibody

RD75133A
Reddot Biotech
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCRTAM
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CRTAM Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.3 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID56253
  • Target name
    CRTAM
  • Target description
    cytotoxic and regulatory T cell molecule
  • Target synonyms
    CD355; class-I MHC-restricted T-cell-associated molecule; cytotoxic and regulatory T-cell molecule
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203