CRTC3 Antibody, Biotin conjugated

Cusabio

CRTC3 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

CRTC3

CREB regulated transcription coactivator 3

CREB-regulated transcription coactivator 3; TORC3; TORC-3; transducer of regulated cAMP response element-binding protein (CREB) 3; transducer of regulated CREB protein 3

Rabbit

IgG

CREB-regulated transcription coactivator 3

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \Ser-133\ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Human

-20°C or -80°C

12352203