Bio-Connect

CSB antibody [N2C1], Internal

GTX104589
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetERCC6
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CSB antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.69 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2074
  • Target name
    ERCC6
  • Target description
    ERCC excision repair 6, chromatin remodeling factor
  • Target synonyms
    ARMD5, CKN2, COFS, COFS1, CSB, CSB-PGBD3, POF11, RAD26, UVSS1, DNA excision repair protein ERCC-6, ERCC6-PGBD3 fusion protein, ATP-dependent helicase ERCC6, Chimeric CSB-PGBD3 protein, Chimeric ERCC6-PGBD3 protein, Cockayne syndrome group B protein, cockayne syndrome protein CSB, excision repair cross-complementation group 6, excision repair cross-complementing rodent repair deficiency, complementation group 6
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ03468
  • Protein Name
    DNA excision repair protein ERCC-6
  • Scientific Description
    This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Wie M, Khim KW, Groehler Iv AS, et al. Alkylation of nucleobases by 2-chloro-N,N-diethylethanamine hydrochloride (CDEAH) sensitizes PARP1-deficient tumors. NAR Cancer. 2023,5(3):zcad042. doi: 10.1093/narcan/zcad042
    Read this paper
  • Lin H, Yan Y, Luo Y, et al. IP(6)-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion. Nat Commun. 2021,12(1):2461. doi: 10.1038/s41467-021-22941-3
    Read this paper