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CSB antibody [N2C1], Internal

GTX104589
GeneTex
TargetERCC6
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    CSB antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Concentration
    0.69 mg/ml
  • Formulation
    Liquid
  • Gene ID2074
  • Target name
    ERCC6
  • Target description
    ERCC excision repair 6, chromatin remodeling factor
  • Target synonyms
    ARMD5; ATP-dependent helicase ERCC6; Chimeric CSB-PGBD3 protein; Chimeric ERCC6-PGBD3 protein; CKN2; Cockayne syndrome group B protein; cockayne syndrome protein CSB; COFS; COFS1; CSB; CSB-PGBD3; DNA excision repair protein ERCC-6; ERCC6-PGBD3 fusion protein; excision repair cross-complementation group 6; excision repair cross-complementing rodent repair deficiency, complementation group 6; POF11; RAD26; UVSS1
  • Protein IDQ03468
  • Protein Name
    DNA excision repair protein ERCC-6
  • Scientific Description
    This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • IP6-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion. Lin H et al., 2021 Apr 28, Nat Commun
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