Immunohistochemistry of paraffin-embedded Human lung cancer tissue using c-Fms Polyclonal Antibody at dilution 1:45
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using c-Fms Polyclonal Antibody at dilution 1:45
CSF1R Polyclonal Antibody
E-AB-12561
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCSF1R Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.4mg/ml
- Scientific DescriptionThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.
- UNSPSC12352203