Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSTB Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSTB Polyclonal Antibody at dilution 1:30
CSTB Polyclonal Antibody
E-AB-13179
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCSTB Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.9mg/ml
- Scientific DescriptionThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
- UNSPSC12352203