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CTHRC1 (human) (rec.)

AG-40B-0157
AdipoGen Life Sciences
Protein IDQ96CG8
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    CTHRC1 (human) (rec.)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Concentration
    0.1 mg/ml
  • Estimated Purity
    >90%
  • Protein IDQ96CG8
  • Protein Name
    Collagen triple helix repeat-containing protein 1
  • Scientific Description
    Collagen triple helix repeat containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. CTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, in the hypothalamus, pituitary gland and remodeling tissues. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with cancer invasion and metastasis. With adiponectin and other members of the C1q/TNF-related protein (CTRP) family, CTHRC1 shares the presence of a short N-terminal collagen domain but it lacks the characteristic C1q domain that defines the CTRP family of proteins. A recent study identifies CTHRC1 as a novel circulating hormone with metabolic effects. - Protein. Human CTHRC1 (aa 31-243) is fused at the N-terminus to a FLAG®-tag. Source: CHO cells. Endotoxin content: 90% (SDS-PAGE). Collagen triple helix repeat containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. CTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, in the hypothalamus, pituitary gland and remodeling tissues. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with cancer invasion and metastasis. With adiponectin and other members of the C1q/TNF-related protein (CTRP) family, CTHRC1 shares the presence of a short N-terminal collagen domain but it lacks the characteristic C1q domain that defines the CTRP family of proteins. A recent study identifies CTHRC1 as a novel circulating hormone with metabolic effects.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352202

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