CTLA4 / CD152 Antibody (clone ANC152.2/8H5, Biotin)

LifeSpan BioSciences

CTLA4 / CD152 Antibody (clone ANC152.2/8H5, Biotin)

14

CTLA-4 expressed on activated T cells.

Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab)2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.. ELISA, Flo, Func Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab)2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Functional Assay, Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANC152.2/8H5

1 mg/ml

Biotin

...

CTLA4

cytotoxic T-lymphocyte associated protein 4

ALPS5; CD; CD152; celiac disease 3; CELIAC3; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; GRD4; GSE; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

Mouse

IgG1

Human

2°C to 8°C

12352203