CTLA4 / CD152 Antibody (clone ANC152.2/8H5)

LifeSpan BioSciences

CTLA4 / CD152 Antibody (clone ANC152.2/8H5)

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CTLA-4 expressed on activated T cells.

Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab)2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model.. ELISA, Flo, Func Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab)2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model.

Functional Assay, Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANC152.2/8H5

1 mg/ml

Unconjugated

...

CTLA4

cytotoxic T-lymphocyte associated protein 4

ALPS5; CD; CD152; celiac disease 3; CELIAC3; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; GRD4; GSE; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

Mouse

IgG1

Human

2°C to 8°C

12352203