CTPB [586976-24-1]

Name: CTPB [586976-24-1]
SKU: AG-CR1-0141_A27
Price: 47 EUR
Availability: BackOrder

AG-CR1-0141

CAS Number586976-24-1

Product group Chemicals

Estimated Purity>98%

Molecular Weight554.1

Overview

Supplier
AdipoGen Life Sciences
Product Name
CTPB [586976-24-1]
Delivery Days Customer
10
CAS Number
586976-24-1
Certification
Research Use Only
Estimated Purity
>98%
Molecular Formula
C31H43ClF3NO2
Molecular Weight
554.1
Scientific Description
Chemical. CAS: 586976-24-1. Formula: C31H43ClF3NO2. MW: 554.1. Potent activator of p300 HAT (histone acetyltransferase) activity, which has an important role in regulation of gene expression. Does not show PCAF (p300/CBP-associated factor) HAT activities. Membrane-impermeable that requires a carrier to pass the membrane barrier of cells. - Potent activator of p300 HAT (histone acetyltransferase) activity, which has an important role in regulation of gene expression. Does not show PCAF (p300/CBP-associated factor) HAT activities. Membrane-impermeable that requires a carrier to pass the membrane barrier of cells.
SMILES
CCCCCCCCCCCCCCCC1=C(C(=O)NC2=CC(=C(Cl)C=C2)C(F)(F)F)C(OCC)=CC=C1
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352200

Small molecule modulators of histone acetyltransferase p300: K. Balasubramanyam, et al.; J. Biol. Chem. 278, 19134 (2003)
Activation of p300 histone acetyltransferase by small molecules altering enzyme structure: probed by surface-enhanced Raman spectroscopy: K. Mantelingu, et al.; J. Phys. Chem. B. 111, 4527 (2007)
Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities: J.A. Souto, et al.; ChemMedChem 3, 1435 (2008)
Intrinsically fluorescent carbon nanospheres as a nuclear targeting vector: delivery of membrane-impermeable molecule to modulate gene expression in vivo: B.R. Selvi, et al.; Nano Lett. 8, 3182 (2008)
Exploring the binding affinities of p300 enzyme activators CTPB and CTB using docking method: B. Devipriya, et al.; Indian J. Biochem. Biophys. 47, 364 (2010)
Charge density distribution and the electrostatic moments of CTPB in the active site of p300 enzyme: a DFT and charge density study: B. Devipriya & P. Kumaradhas; J. Theor. Biol. 335, 119 (2013)