CTTN Polyclonal Antibody
RD81988A
TargetCTTN
Product group Antibodies
Overview
- SupplierReddot Biotech
- Product NameCTTN Polyclonal Antibody
- Delivery Days Customer5
- Concentration1 mg/ml
- Gene ID2017
- Target nameCTTN
- Target descriptioncortactin
- Target synonyms1110020L01Rik; amplaxin; EMS1; ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate); epididymis secretory sperm binding protein; oncogene EMS1; src substrate cortactin
- Scientific DescriptionThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.
- Storage Instruction-20°C
- UNSPSC12352203