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CU-115

HY-131945
MedChem Express
CAS Number2471982-20-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.55
Molecular Weight569.21
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CU-115 [2471982-20-2]
  • Delivery Days Customer
    10
  • CAS Number
    2471982-20-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.55
  • Molecular Formula
    C21H11F7INO2
  • Molecular Weight
    569.21
  • Scientific Description
    CU-115 is a potent TLR8 antagonist (IC50=1.04 microM), and shows selective for TLR8 over TLR7 (IC50=>50 microM). CU-115 decreases TNF-alpha and IL-1beta production activated by R-848 in THP-1 cells[1].
  • SMILES
    O=C(NC1=CC=C(OC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C=C1)C3=C(I)C=CC=C3F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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