Cucurbitacin B

Bioss Antibodies

Cucurbitacin B [6199-67-3]

16

Research Use Only

>98%

Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation. Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties. Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell lines. Shown to inhibit STAT 3 phosphorylation and expression levels and blocks JAK2 activity, as well as the transcriptional activity of HIF1alpha and NF-kappaB. Antioxidant. Serves as an ecdysteroid receptor antagonist in Drosophila.

-20°C

51202000