GTX111041 ICC/IF Image
Cullin 5 antibody [N1N2], N-term
GTX111041
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCullin 5 antibody [N1N2], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.91 mg/ml
- IsotypeIgG
- Scientific DescriptionCore component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. Seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203