anti-Protein C antibody [HLW-C]
ARG10089
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetPROC
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Protein C antibody [HLW-C]
- Delivery Days Customer23
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHLW-C
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5624
- Target namePROC
- Target descriptionprotein C, inactivator of coagulation factors Va and VIIIa
- Target synonymsactivated protein C; anticoagulant protein C; APC; autoprothrombin IIA; blood coagulation factor XIV; PC; prepro-protein C; PROC1; Protein C-Nagoya; THPH3; THPH4; type I protein C; vitamin K-dependent protein C
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionProtein C is a vitamin K dependant glycoprotein in blood. Activated Protein C (APC) functions as an anti-coagulation factor in blood by proteolyzing pro-coagulation factors including Factor V and Factor VIII. When bound with endothelial protein C receptor (EPCR) on vascular endothelial cells, APC acts on protease activated receptor I (PAR-1) to up-regulate the expression of genes involved with anti-inflammatory and anti- apoptotic pathways, thus it also possesses a cell protective function. Protein C is activated by binding with thrombin. The activation is enhanced by thrombomodulin and EPCR.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203