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Bafetinib

Research Use Only
HY-50868
MedChem Express
CAS Number859212-16-1
Product group Chemicals
Estimated Purity99.77
Molecular Weight576.62
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Bafetinib [859212-16-1]
  • Delivery Days Customer
    10
  • CAS Number
    859212-16-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.77
  • Molecular Formula
    C30H31F3N8O
  • Molecular Weight
    576.62
  • Scientific Description
    Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity[1][2][3].
  • SMILES
    O=C(C1=CC=C(C(C(F)(F)F)=C1)CN2C[C@@H](N(C)C)CC2)NC3=CC=C(C)C(NC4=NC=CC(C5=CN=CN=C5)=N4)=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200