BECN1 Antibody, Biotin conjugated
CSB-PA617917LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetBECN1
Overview
- SupplierCusabio
- Product NameBECN1 Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- Gene ID8678
- Target nameBECN1
- Target descriptionbeclin 1
- Target synonymsATG6; ATG6 autophagy related 6 homolog; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; coiled-coil myosin-like BCL2-interacting protein; testis secretory sperm-binding protein Li 215e; VPS30
- HostRabbit
- IsotypeIgG
- Protein IDQ14457
- Protein NameBeclin-1
- Scientific DescriptionPlays a central role in autophagy (PubMed:23184933). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203