WB analysis of Daudi lysate using GTX89949 BLNK antibody, C-term. Dilution : 4microg/ml Loading : 30microg protein in RIPA buffer
BLNK antibody, C-term
GTX89949
Overview
- SupplierGeneTex
- Product NameBLNK antibody, C-term
- Delivery Days Customer9
- Antibody SpecificityThis antibody is expected to recognize both reported isoforms (NP_037446.1; NP_001107566.1).
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID29760
- Target nameBLNK
- Target descriptionB cell linker
- Target synonymsAGM4; B cell adaptor containing SH2 domain; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; BLNK-S; cytoplasmic adapter protein; LY57; SLP65; SLP-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
- HostGoat
- IsotypeIgG
- Scientific DescriptionThis gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203