BVES Antibody
CSB-PA002887ESR1HU
ApplicationsImmunoFluorescence, ELISA
Product group Antibodies
ReactivityHuman
TargetBVES
Overview
- SupplierCusabio
- Product NameBVES Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11149
- Target nameBVES
- Target descriptionblood vessel epicardial substance
- Target synonymsblood vessel epicardial substance; CARICK; HBVES; LGMD2X; LGMDR25; POP1; POPDC1; popeye domain-containing protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ8NE79
- Protein NameBlood vessel epicardial substance
- Scientific DescriptionCell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203