WB analysis of (1) K562, (2) U937 and (3) THP-1 lysates (10 microg per lane) using Cdc25B antibody [EPR3459(2)] at a dilution of 1:1,000.
CDC25B antibody [EPR3459(2)]
GTX63329
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetCDC25B
Overview
- SupplierGeneTex
- Product NameCDC25B antibody [EPR3459(2)]
- Delivery Days Customer9
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDEPR3459(2)
- ConjugateUnconjugated
- Gene ID994
- Target nameCDC25B
- Target descriptioncell division cycle 25B
- Target synonymsCDC25 homolog B; dual specificity phosphatase Cdc25B; M-phase inducer phosphatase 2
- HostRabbit
- IsotypeIgG
- Scientific DescriptionCDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Fanconi anemia cells with unrepaired DNA damage activate components of the checkpoint recovery process. Rodriguez A et al., 2015 Sep 18, Theor Biol Med ModelRead more