CTRP1 antibody

GeneTex

CTRP1 antibody

9

These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

C1QTNF1

C1q and TNF related 1

C1q and tumor necrosis factor related protein 1; complement C1q tumor necrosis factor-related protein 1; CTRP1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; GIP; ZSIG37

Rabbit

IgG

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice (3).

Human, Mouse, Rat

2°C to 8°C,-20°C or -80°C

12352203