Endothelin B Receptor antibody [N1N2], N-term

GeneTex

Endothelin B Receptor antibody [N1N2], N-term

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

EDNRB

endothelin receptor type B

ABCDS; endothelin receptor non-selective type; endothelin receptor subtype B1; endothelin receptor type B; ETB; ET-B; ETB1; ETBR; ET-BR; ETRB; Hirschsprung disease 2; HSCR; HSCR2; WS4A

Rabbit

IgG

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq]

Human

2°C to 8°C,-20°C or -80°C

12352203