EPZ005687

Biorbyt

EPZ005687 [1396772-26-1]

16

1396772-26-1

Research Use Only

C32H37N5O3

539.6679

EPZ-005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.

O1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])([H])C1C([H])=C([H])C(=C([H])C=1[H])C1=C([H])C(C(N([H])C([H])([H])C2C(N([H])C(C([H])([H])[H])=C([H])C=2C([H])([H])[H])=O)=O)=C2C([H])=NN(C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]

12352200