IL-22 (mouse) (rec.) (His)
![Research Use Only](static/images/certificates/ruo.jpg)
CHI-MR-10022
Product group Proteins / Signaling Molecules
Overview
- SupplierChimerigen Laboratories
- Product NameIL-22 (mouse) (rec.) (His)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionInterleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rbeta(CRF24), belonging to the class II cytokine receptor family. - Protein. Mouse IL-22 (aa 34-179) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: <1EU/microg protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS. Purity: >95% (SDS-PAGE). Interleukin-22 (IL-22), also known as IL-10 related T cell-derived-inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rbeta(CRF24), belonging to the class II cytokine receptor family.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202