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KHDRBS2 Antibody, Biotin conjugated

Research Use Only
CSB-PA730139LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetKHDRBS2
Price on request
Packing Size
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Overview

  • Supplier
    Cusabio
  • Product Name
    KHDRBS2 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID202559
  • Target name
    KHDRBS2
  • Target description
    KH RNA binding domain containing, signal transduction associated 2
  • Target synonyms
    KH domain containing, RNA binding, signal transduction associated 2; KH domain-containing, RNA-binding, signal transduction-associated protein 2; Sam68-like mammalian protein 1; SLM1; SLM-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ5VWX1
  • Protein Name
    KH domain-containing, RNA-binding, signal transduction-associated protein 2
  • Scientific Description
    RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203