KIF14 Antibody, Biotin conjugated
CSB-PA613582LD01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetKIF14
Overview
- SupplierCusabio
- Product NameKIF14 Antibody, Biotin conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateBiotin
- Gene ID9928
- Target nameKIF14
- Target descriptionkinesin family member 14
- Target synonymsepididymis secretory sperm binding protein; kinesin-like protein KIF14; MCPH20; MKS12
- HostRabbit
- IsotypeIgG
- Protein IDQ15058
- Protein NameKinesin-like protein KIF14
- Scientific DescriptionMicrotubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203