Kiss1 antibody
GTX130503
Overview
- SupplierGeneTex
- Product NameKiss1 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.25 mg/ml
- ConjugateUnconjugated
- Gene ID3814
- Target nameKISS1
- Target descriptionKiSS-1 metastasis suppressor
- Target synonymsHH13; KiSS-1; kisspeptin-1; malignant melanoma metastasis-suppressor; metastasis-suppressor KiSS-1; metastin; prepro-kisspeptin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq]
- ReactivityHuman, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203