Flow Cytometry analysis of LAT expression in peripheral blood lymphocytes using anti-human LAT (GTX22852) (surface markers were stained prior to intracellular staining of human LAT). Panel A: gate on CD4+ cells Panel B: gate on CD8+ cells
Flow Cytometry analysis of LAT expression in peripheral blood lymphocytes using anti-human LAT (GTX22852) (surface markers were stained prior to intracellular staining of human LAT). Panel A: gate on CD4+ cells Panel B: gate on CD8+ cells
LAT antibody [LAT-01]
GTX22852
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetLAT
Overview
- SupplierGeneTex
- Product NameLAT antibody [LAT-01]
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Mouse.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDLAT-01
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID27040
- Target nameLAT
- Target descriptionlinker for activation of T cells
- Target synonyms36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; IMD52; LAT1; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells family member 1; p36-38; pp36
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203