Phospho-EIF2AK2 (Thr446) Antibody

Cusabio

Phospho-EIF2AK2 (Thr446) Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

EIF2AK2

eukaryotic translation initiation factor 2 alpha kinase 2

double stranded RNA activated protein kinase; eIF-2A protein kinase 2; EIF2AK1; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; LEUDEN; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; PRKR; protein kinase R; protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; tyrosine-protein kinase EIF2AK2

Rabbit

IgG

Interferon-induced, double-stranded RNA-activated protein kinase

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. Abujiang Pataer, et,al. (2002) Cancer Res; 62: 2239. K. D. Ryman, et,al. (2005) J. Virol; 79: 1487 - 1499. Susana Guerra, et,al. (2006) J. Biol. Chem; 281: 18734 - 18745.

Human, Mouse

-20°C or -80°C

12352203