ICC/IF analysis of methanol-fixed HeLa cells using GTX38559 PLCG2 (phospho Tyr753) antibody.
ICC/IF analysis of methanol-fixed HeLa cells using GTX38559 PLCG2 (phospho Tyr753) antibody.
PLCG2 (phospho Tyr753) antibody
GTX38559
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetPLCG2
Overview
- SupplierGeneTex
- Product NamePLCG2 (phospho Tyr753) antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody detects endogenous levels of PLC gamma 2 only when phosphorylated at tyrosine 753.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5336
- Target namePLCG2
- Target descriptionphospholipase C gamma 2
- Target synonyms1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C-gamma-2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-IV; PLC-gamma-2; PLC-IV
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203