RNASEH1 Polyclonal Antibody
RD268012A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRNASEH1
Overview
- SupplierReddot Biotech
- Product NameRNASEH1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID246243
- Target nameRNASEH1
- Target descriptionribonuclease H1
- Target synonymsH1RNA; PEOB2; ribonuclease H type II; ribonuclease H1; RNH1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes; two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203