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RVX-297

Research Use Only
HY-114504
MedChem Express
CAS Number1044871-04-6
DownloadMSDS
Product group Chemicals
Estimated Purity95.00
Molecular Weight423.50
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RVX-297 [1044871-04-6]
  • Delivery Days Customer
    10
  • CAS Number
    1044871-04-6
  • Certification
    Research Use Only
  • Estimated Purity
    95.00
  • Molecular Formula
    C24H29N3O4
  • Molecular Weight
    423.50
  • Scientific Description
    RVX-297 is a potent, orally active BET bromodomain inhibitor with selectivity for BD2. RVX-297 shows IC50s of 0.08, 0.05, and 0.02 microM for BRD2(BD2), BRD3(BD2), and BRD4(BD2), respectively. RVX-297 suppresses inflammatory gene expression in multiple immune cell types. RVX-297 is effective in acute inflammation and autoimmunity models[1][2].
  • SMILES
    O=C1NC(C2=CC(C)=C(OCCN3CCCC3)C(C)=C2)=NC4=C1C(OC)=CC(OC)=C4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200