SB-334867
HY-10895
Overview
- SupplierMedChem Express
- Product NameSB-334867 [249889-64-3]
- Delivery Days Customer10
- CAS Number249889-64-3
- CertificationResearch Use Only
- Estimated Purity99.44
- Molecular FormulaC17H14ClN5O2
- Molecular Weight355.78
- Scientific DescriptionSB-334867 (SB 334867A) is an excellent,selective and blood-brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively[1]. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo[2][3].
- SMILESO=C(NC1=CC(OC(C)=N2)=C2C=C1)NC3=CC=NC4=CC=CN=C43.Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200