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ProductsBack/SLUG antibody - Overexpression Validated
IHC-P analysis of human kidney tissue using GTX30813 SLUG antibody. Dilution : 20 microg/ml
IHC-P analysis of human kidney tissue using GTX30813 SLUG antibody. Dilution : 20 microg/ml
IHC-P analysis of human kidney tissue using GTX30813 SLUG antibody. Dilution : 20 microg/ml

SLUG antibody - Overexpression Validated

Research Use Only
GTX30813
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetSNAI2
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Overview

  • Supplier
    GeneTex
  • Product Name
    SLUG antibody - Overexpression Validated
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody detects Slug and is not cross-reactive with Snail.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6591
  • Target name
    SNAI2
  • Target description
    snail family transcriptional repressor 2
  • Target synonyms
    neural crest transcription factor SLUG; protein snail homolog 2; SLUG; slug (chicken homolog), zinc finger protein; SLUGH; SLUGH1; snail family zinc finger 2; snail homolog 2; SNAIL2; WS2D; zinc finger protein SNAI2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Fibroblast growth factor 2 induces proliferation and fibrosis via SNAI1-mediated activation of CDK2 and ZEB1 in corneal endothelium. Lee JG et al., 2018 Mar 9, J Biol Chem
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  • Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells. Lee AF et al., 2017, PLoS One
    Read more