TNFRSF11B Polyclonal Antibody
RD70277A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetTnfrsf11b
Overview
- SupplierReddot Biotech
- Product NameTNFRSF11B Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.93 mg/ml
- ConjugateUnconjugated
- Gene ID18383
- Target nameTnfrsf11b
- Target descriptiontumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
- Target synonymsO; OC; OCIF; Opg; osteoclastogenesis inhibitory factor; osteoprotegerin; TR; TR1; tumor necrosis factor receptor superfamily member 11B
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203