VGLUT1 Antibody (OASE00242)
OASE00242
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSlc17a7
Overview
- SupplierAviva Systems Biology
- Product NameVGLUT1 Antibody (OASE00242)
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDS28-9
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormatLiquid. PBS, pH 7.4 with 50% glycerol and 0.09% sodium azide.
- Gene ID116638
- Target nameSlc17a7
- Target descriptionsolute carrier family 17 member 7
- Target synonymsBNPI; brain-specific Na(+)-dependent inorganic phosphate cotransporter; brain-specific Na-dependent inorganic phosphate cotransporter; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; solute carrier family 17 (vesicular glutamate transporter), member 7; vesicular glutamate transporter 1; Vglut1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionVGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate (1). Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate (2).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203